Table 2 Cluster information of seed-based connectivity analyses.

Seed: contrast Labeled brain region	Peak voxel coordinates			cluster size	beta	T-value	p-cFWE
	x	y	z
Seed: Posterior cingulate cortex (postflight > preflight) (df = 14)
No significant results
Seed: Posterior cingulate cortex (preflight > postflight) (df = 14)
No significant results
Seed: Thalamus (sustained increases: contrast [−1 0.5 0.5]) (df = 10)
No significant results
Seed: Thalamus (sustained decreases: contrast [1 −0.5 −0.5]) (df = 10)
Superior frontal gyrus, R	24	26	40	348	0.14	7.07	<0.001
Superior frontal gyrus, L	−14	38	52	251	0.18	6.42	0.008
Seed: Angular gyrus, R (sustained increases: contrast [−1 0.5 0.5]) (df = 10)
Angular gyrus, L	−32	−64	54	178	0.17	6.78	0.044
Inferior frontal gyrus (pars triangularis), L	−32	38	04	176	0.17	6.39	0.047
Seed: Angular gyrus, R (sustained decreases: contrast [1 −0.5 −0.5]) (df = 10)
Precentral gyrus, R	40	−04	58	990	0.16	9.09	<0.001
Postcentral gyrus, L	−32	−40	64	681	0.15	7.30	<0.001
Postcentral gyrus, L	−44	−22	48	205	0.14	6.77	0.021
Seed: bilateral insula (normalized increases: contrast [−0.5 1 −0.5]) (df = 10)
Angular gyrus, L	−26	−80	42	195	0.14	5.42	0.044
Seed: bilateral insula (normalized increases: contrast [0.5 −1 0.5]) (df = 10)
Precentral gyrus (medial), R	18	−34	36	2769	0.13	9.15	<0.001
Central operculum, L	−50	02	−02	263	0.15	7.41	0.008
Central operculum, R	54	−02	18	259	0.15	6.99	0.009
Planum temporale, L	−68	−26	34	258	0.15	7.08	0.009
Supramarginal gyrus, R	48	−32	36	227	0.15	5.65	0.019

A seed-based connectivity analysis was run with the resulting clusters from the global connectivity analysis as seed regions. The contrast tested is included for each of the seeds. Beta values represent a measure for effect size; T-values are cluster-averaged; p-cFWE is the p-value after cluster-wise family-wise error (FWE) correction. This threshold was set at p < 0.05. Bold fonts are used as headers to define the exact test that was performed.

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