Table 1 DEPs in THRSP KO mice involved in Wnt signaling.
Expression | Mapped IDs | Name/Symbo006C | Fold change | P value |
|---|---|---|---|---|
Upregulated | Gnb4 | Guanine nucleotide-binding protein subunit beta-4; GNB4; ortholog | 1.7868 | 0.0011 |
Arrb1 | Beta-arrestin-1; ARRB1; ortholog | 1.3168 | 0.0040 | |
Gnb1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; GNB1; ortholog | 1.3159 | 0.0041 | |
Tbl1xr1 | F-box-like/WD repeat-containing protein TBL1XR1; TBL1XR1; ortholog | 1.2978 | 0.0055 | |
Gnb2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; GNB2; ortholog | 1.2958 | 0.0055 | |
Cdh2 | Cadherin-2; CDH2; ortholog | 1.2180 | 0.0069 | |
Adss1 | Adenylosuccinate synthetase isozyme 1; ADSS1; ortholog | 1.1574 | 0.0094 | |
Smarcc2 | SWI/SNF complex subunit SMARCC2; SMARCC2; ortholog | 1.1382 | 0.0100 | |
Csnk2a2 | Casein kinase II subunit alpha’; CSNK2A2; ortholog | 1.0677 | 0.0139 | |
Smarcd1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1; SMARCD1; ortholog | 1.0421 | 0.0154 | |
Myh7b | Myosin-7B; MYH7B; ortholog | 0.9661 | 0.0216 | |
Ctbp1 | C-terminal-binding protein 1; CTBP1; ortholog | 0.9419 | 0.0238 | |
Cdh4 | Cadherin-4; CDH4; ortholog | 0.8791 | 0.0287 | |
Smarcb1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; SMARCB1; ortholog | 0.8791 | 0.0287 | |
Downregulated | Adss2 | Adenylosuccinate synthetase isozyme 2; ADSS2; ortholog | –0.9112 | 0.0249 |
Ppp3r1 | Calcineurin subunit B type 1; PPP3R1; ortholog | –0.9115 | 0.0248 | |
Ctnna2 | Catenin alpha-2; CTNNA2; ortholog | –0.9199 | 0.0244 | |
Prkcb | Protein kinase C beta type; PRKCB; ortholog | –1.0276 | 0.0153 | |
Smarca4 | Transcription activator BRG1; SMARCA4; ortholog | –1.0439 | 0.0147 | |
Itpr1 | Inositol 1,4,5-trisphosphate receptor type 1; ITPR1; ortholog | –1.0551 | 0.0139 | |
Pcdh19 | Protocadherin-19;PCDH19;ortholog | –1.1412 | 0.0093 | |
Gng2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; GNG2; ortholog | –1.2217 | 0.0063 | |
Csnk1g1 | Casein kinase I isoform gamma-1; CSNK1G1; ortholog | –1.2269 | 0.0062 | |
Ppp3cc | Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform; PPP3CC; ortholog | –2.0380 | 0.0005 | |
Prkce | Protein kinase C epsilon type; PRKCE; ortholog | –2.2312 | 0.0003 | |
Prkca | Protein kinase C alpha type; PRKCA; ortholog | –2.3693 | 0.0002 | |
Gng12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; GNG12; ortholog | –2.6507 | 0.0001 | |
Acta2 | Actin, aortic smooth muscle; ACTA2; ortholog | –2.8117 | 0.0001 | |
Gng3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3; GNG3; ortholog | –2.8255 | 0.0001 | |
Ppp3ca | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; PPP3CA; ortholog | –2.8295 | 0.0001 | |
Ppp3cb | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform; PPP3CB; ortholog | –3.6034 | 0.0000 | |
Gng7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7; GNG7; ortholog | –3.6163 | 0.0000 | |
Actc1 | Actin, alpha cardiac muscle 1; ACTC1; ortholog | –5.3626 | 0.0000 | |
Actg1 | Actin, cytoplasmic 2; ACTG1; ortholog | –5.5769 | 0.0000 | |
Actb | Actin, cytoplasmic 1; ACTB; ortholog | –5.7398 | 0.0000 |
