Table 2 DEPs in THRSP OE mice involved in Wnt signaling.
Expression | Mapped IDs | Name/symbol | Fold change | P value |
|---|---|---|---|---|
Upregulated | Ctnna1 | Catenin alpha-1; CTNNA1; ortholog | 1.6630 | 0.0016 |
Smarcc2 | SWI/SNF complex subunit SMARCC2; SMARCC2; ortholog | 1.6549 | 0.0016 | |
Acvr1b | Activin receptor type-1B; ACVR1B; ortholog | 1.5138 | 0.0021 | |
Ctnna2 | Catenin alpha-2; CTNNA2; ortholog | 1.4648 | 0.0024 | |
Prkcd | Protein kinase C delta type; PRKCD; ortholog | 1.2855 | 0.0045 | |
Ctnnb1 | Catenin beta-1; CTNNB1; ortholog | 1.2173 | 0.0057 | |
Hdac2 | Histone deacetylase 2; HDAC2; ortholog | 1.1406 | 0.0085 | |
Apc | Adenomatous polyposis coli protein; APC; ortholog | 0.9016 | 0.0239 | |
Myh7b | Myosin-7B; MYH7B; ortholog | 0.8628 | 0.0287 | |
Downregulated | Acta2 | Actin, aortic smooth muscle; ACTA2; ortholog | –0.5124 | 0.0125 |
Arhgef6 | Rho guanine nucleotide exchange factor 6; ARHGEF6; ortholog | –0.8640 | 0.0281 | |
Gng3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3; GNG3; ortholog | –1.0286 | 0.0137 | |
Ppp2cb | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; PPP2CB; ortholog | –1.0362 | 0.0135 | |
Csnk1g1 | Casein kinase I isoform gamma-1; CSNK1G1; ortholog | –1.0397 | 0.0133 | |
Gng7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7; GNG7; ortholog | –1.0665 | 0.0122 | |
Smarca4 | Transcription activator BRG1; SMARCA4; ortholog | –1.1084 | 0.0094 | |
Prkcb | Protein kinase C beta type; PRKCB; ortholog | –1.1734 | 0.0076 | |
Gng12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; GNG12; ortholog | –1.1861 | 0.0071 | |
Gnb2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; GNB2; ortholog | –1.3393 | 0.0037 | |
Smarcal1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; SMARCAL1; ortholog | –1.3419 | 0.0037 | |
Gnb1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; GNB1; ortholog | –1.4755 | 0.0024 | |
Actb | Actin, cytoplasmic 1; ACTB; ortholog | –1.5119 | 0.0022 | |
Gnb4 | Guanine nucleotide-binding protein subunit beta-4; GNB4; ortholog | –1.5291 | 0.0021 | |
Cdh9 | Cadherin-9; CDH9; ortholog | –1.5912 | 0.0018 | |
Actg1 | Actin, cytoplasmic 2; ACTG1; ortholog | –1.6339 | 0.0017 | |
Csnk1a1 | Casein kinase I isoform alpha; CSNK1A1; ortholog | –1.8498 | 0.0011 | |
Ppp3ca | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; PPP3CA; ortholog | –1.9689 | 0.0009 | |
Prkca | Protein kinase C alpha type; PRKCA; ortholog | –1.9847 | 0.0009 | |
Prkcg | Protein kinase C gamma type; PRKCG; ortholog | –2.1606 | 0.0007 | |
Actc1 | Actin, alpha cardiac muscle 1; ACTC1; ortholog | –2.4216 | 0.0004 | |
Ppp3cb | Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform; PPP3CB; ortholog | –2.6280 | 0.0003 |
