Fig. 3: Functional analysis of the host proteins targeted by the plant virus TuMV.
From: A binary interaction map between turnip mosaic virus and Arabidopsis thaliana proteomes
a Representation in a semantic space of the functional categories (related to biological processes) enriched within the virus targets. Bubble size scales with the total number of proteins per category. Statistical significance assessed by Fisher exact tests, 2 × 2 tables, FDR adjusted P < 0.05. b Heat map for the main functions (related to metabolism, development, organization, signaling, regulation, and defense) targeted by each TuMV protein. Color scale indicates fraction relative to the total number of targets of that virus protein. c Principal component analysis of the data shown in panel b. The different virus proteins are distributed in this space according to the similarity of the functional overlap of their targets. d Associative mapping between the function of each virus protein (in the context of viral processes) and the main functions of each virus target (in the context of plant physiology).
