Fig. 8: TuMV-interacting host proteins are evolutionarily conserved hubs.
From: A binary interaction map between turnip mosaic virus and Arabidopsis thaliana proteomes
a Phylogeny of the three species used for the population study. b Comparison between the actual pN/pS distribution [computed as pN/(pS + 1) to account for genes with pS = 0] and a representative null distribution (from randomly picked genes). *Statistical significance (Mann–Whitney U test, P < 0.05). The inset shows the distribution of P values after 1000 random realizations, with geometric mean 0.0016. c Comparison between the actual DoS distribution and a representative null distribution (from randomly picked genes). nsStatistically non-significant (Mann–Whitney U test, P > 0.05). The inset shows the distribution of P values after 103 random realizations, with geometric mean 0.0654. d Top five host factors with DoS > 0 (positive selection) and DoS < 0 (negative selection), together with their interacting virus proteins. e Species tree generated by OrthoFinder. The branch of interest, used in the CODEML analysis, is the green branch leading to the Arabidopsis genus. f Comparison between the actual ω distribution and a representative null distribution (from randomly picked genes). *Statistical significance (Mann–Whitney U test, P < 0.05). The inset shows the distribution of P values after 1000 random realizations, with geometric mean 0.0043.
