Fig. 1: circCEBPZOS was significantly downregulated in the serum EVs of patients with postinfarct cardiac remodeling. | Communications Biology

Fig. 1: circCEBPZOS was significantly downregulated in the serum EVs of patients with postinfarct cardiac remodeling.

From: Extracellular vesicle-derived circCEBPZOS attenuates postmyocardial infarction remodeling by promoting angiogenesis via the miR-1178-3p/PDPK1 axis

Fig. 1

a Venn diagram to present the number of differentially expressed circRNAs among the serum exosomes from patients with and without postinfarct cardiac remodeling using whole transcriptome sequencing. b, c Heatmap and volcano plot to present the expression of differentially expressed circRNAs, respectively. d Phenotype of exosomes isolated from serum from patients with and without postinfarct cardiac remodeling by transmission electron microscopy, Bar = 100 μm; the particle size of exosomes identified by nanoparticle tracking analysis. e Protein expression of CD6, CD9 and TSG101 was detected using western blotting. f Expression of hsa_circ_0000212, hsa_circ_0089282 and circCEBPZOS in exosomes from patients with and without postinfarct cardiac remodeling by using divergent primers. GAPDH served as control. Data are mean ± SD. **P < 0.01, N-CR group vs. Control group; ##P < 0.01, CR group vs N-CR group. CR postinfarct cardiac remodeling, N-CR nonpostinfarct cardiac remodeling.

Back to article page