Fig. 9: Expression changes of miR-1178-3p and PDPK1 in vivo treatment with exosomes harboring circCEBPZOS.

a Expression of miR-1178-3p was detected by qRT–PCR, U6 acted as a control; b, c Expression of PDPK1 was detected by qRT–PCR and western blotting. GAPDH served as control. d Immunofluorescence staining was used to detect the expression of PDPK1 in heart tissues. DAPI was used to stain the nuclei; Bar = 50 μm. e ELISA was used to detect the contents of PDPK1.Data are mean ± SD. **P < 0.01, Over-circ-Exo group vs. Model-NC group; ##P < 0.01, She-circ-Exo group vs. Model-NC group.