Fig. 3: CyTOF revealed the regulatory effect of RIN1 on infiltrating T cells in mouse primary HCC. | Communications Biology

Fig. 3: CyTOF revealed the regulatory effect of RIN1 on infiltrating T cells in mouse primary HCC.

From: Targeted inhibition of RBPJ transcription complex alleviates the exhaustion of CD8+ T cells in hepatocellular carcinoma

Fig. 3

a Experimental design and analysis workflow of cyTOF (all the components were from BioRender (https://biorender.com/)). b Frequency of mouse HCC infiltrating CD8+ T cell subpopulations (n = 6). c Expression of selected functional markers on mouse HCC infiltrating CD8+ T cells (n = 6). d Heatmap of corrected median expression of ten T cell subpopulations (n = 6). e t-SNE plot of mouse HCC infiltrating T cells (n = 6). f Comparison of the proportions of ten T cell subpopulations (n = 6). Mean ± SD. Statistical significance determined by paired two-tailed t-test (b, c, e). *P < 0.05; **P < 0.01.

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