Table 1 General characteristics, serum, and urinary biochemistry in WT, Alb-hKL, and Pod-hKL mice at baseline.
From: Soluble Klotho protects against glomerular injury through regulation of ER stress response
WT | Alb-hKL | Pod-hKL | |
|---|---|---|---|
Age—Female (weeks) | 10.7 ± 2.2 | 11.1 ± 1.7 | 12.2 ± 3.5 |
Age—Male (weeks) | 10.4 ± 1.3 | 9.9 ± 0.9 | 9.8 ± 1.6 |
Weight—Female (g) | 21.2 ± 2.1 | 19.9 ± 1.9 | 26.1 ± 4.4 |
Weight—Male (g) | 29.0 ± 2.9 | 26.6 ± 2.2 | 27.0 ± 2.2 |
Female/male | 12/12 | 11/9 | 5/5 |
Serum | n = 14 | n = 10 | n = 4 |
Creatinine (mg/dL) | 0.153 ± 0.04 | 0.183 ± 0.04 | 0.113 ± 0.03 |
Calcium (mg/dL) | 9.49 ± 2.46 | 10.64 ± 2.47 | 10.64 ± 1.18 |
Phosphate (mg/dL) | 10.51 ± 1.67 | 11.60 ± 1.07 | 10.73 ± 2.61 |
Intact Fgf23 (pg/mL) | 139.3 ± 64.8 | 306.1 ± 189.1# | 116.4 ± 19.2 |
Urine | n = 14 | n = 10 | n = 4 |
FECa (%) | 0.43 ± 0.24 | 1.03 ± 0.83 | 0.44 ± 0.40 |
FEPi (%) | 0.53 ± 0.49 | 0.39 ± 0.49 | 0.77 ± 0.04 |
