Fig. 6: Sporontocidal activity of gramicidin.

The figure shows dose-response analyses of gramicidin in sporozoite viability, gliding, traversal, and hepatic schizogony assays. In the latter assay, sporozoites were pre-incubated with gramicidin for 30 min prior to hepatocyte infection, or directly added to the host cells. The figures show data normalized to the respective positive and negative controls in the assays. Each condition was tested in 2–4 replicates.