Fig. 5: Correlation of fibril length obtained from AFM measurements and CSF with patient diagnostic classification.
From: Protein fibril length in cerebrospinal fluid is increased in Alzheimer’s disease
a Combined box and whiskers and violin plots in the style of Tukey of the mean of CSF fibril length per patient group. The mean fibril length was significantly higher in ADD than in MCI and SCD patients as well as higher in MCI AD than SCD patients (Games-Howell pairwise post-hoc tests). b CSF fibril length plotted against the age as a function of the group. Regression lines with 95% CI depict the ‘age x diagnosis’ interaction effect on CSF fibril length based on a linear regression model with the predictors’ age, diagnosis and the interaction ‘age x diagnosis’ fitted for patients with either SCD, MCI AD or ADD (n = 28).
