Fig. 2: Differential proteome analyses of atherosclerotic (unstable and stable) arteries versus healthy, plaque-free arteries. | Communications Biology

Fig. 2: Differential proteome analyses of atherosclerotic (unstable and stable) arteries versus healthy, plaque-free arteries.

From: Quantitative proteomic landscape of unstable atherosclerosis identifies molecular signatures and therapeutic targets for plaque stabilization

Fig. 2

a Hierarchical clustering of differential protein expression across all tissue regions, comparing diseased plaque (stable and unstable) to the healthy vessels (n = 8). Proteins identified in at least 70% within each tissue group (at least 5/8 samples), FDR < 0.05, 32 proteins highly expressed in plaque (purple), 53 proteins lowly expressed in plaque (orange). b Enrichment map of Reactome pathway terms overrepresented in atherosclerotic plaques (stable and unstable) in comparison to healthy arteries.

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