Fig. 3: fH-binding by SdrE involves a DLL-like interaction. | Communications Biology

Fig. 3: fH-binding by SdrE involves a DLL-like interaction.

From: High-force catch bonds between the Staphylococcus aureus surface protein SdrE and complement regulator factor H drive immune evasion

Fig. 3

a Adhesion forces obtained by recording force-distance curves in PBS between three different SdrE(+) cells and fH-tips, in the absence or presence of the C-terminal segment (residues 561–575) of the Fg α-chain (0.5 mg mL−1). b Data obtained for three cells with the C-terminal segment of the Fg Îł-chain (0.5 mg mL−1). The box plot in inset compares the adhesion frequency in the absence (n = 6 cells) and in the presence of either the Fg α-chain (n = 6 cells) or the Fg Îł-chain (n = 5 cells) peptide. **p-value ≀ 0.01; ns not significant, p-value > 0.01, determined by a two-sample t-test in Origin.

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