Fig. 1: The anchoring concept.
From: Extending the use of biologics to mucous membranes by attachment of a binding domain

a Biologics, for example therapeutic antibodies, are rapidly washed out when applied to mucous membranes. b Attaching an anchor to the biologic that binds to the tissue immobilizes the biologic and allows it to act. Here we use wheat germ agglutinin (WGA) which binds to polysaccharides on cell surfaces.