Fig. 7: A proposed model of cPA production by GDE7.
From: GDE7 produces cyclic phosphatidic acid in the ER lumen functioning as a lysophospholipid mediator

GDE7 is activated by Ca2+ in the ER lumen and produces cPA which inhibits the PPARγ pathway.
From: GDE7 produces cyclic phosphatidic acid in the ER lumen functioning as a lysophospholipid mediator
GDE7 is activated by Ca2+ in the ER lumen and produces cPA which inhibits the PPARγ pathway.