Fig. 2: Alternative splicing of haematopoietic transcription factors. | Communications Biology

Fig. 2: Alternative splicing of haematopoietic transcription factors.

From: Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem and progenitor cells

Fig. 2

A Total long-read counts and isoform frequency plot for haematopoietic transcription factors. B Cell-type expression of isoforms of Lmo2. Transcripts are numbered based on their Ensembl isoform suffix. Transcripts in red encode the same protein sequence, while transcripts in black encode distinct proteins. Transcripts in grey are noncoding. C UMAP projection of gene and isoform expression for Lmo2 in haematopoietic cells. D Cell-type expression of isoforms of Gata2. Both major transcripts encode the same protein, although the transcript has an alternative 5’ UTR. E UMAP projection of gene and isoform expression for Gata2 in haematopoietic cells.

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