Table 1 Clinical characteristics of patient cohort.

From: Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survival

 

Short-term (ST)

Long-term (LT)

Patients (no.)

n = 23

n = 16

Tumors

46

32

 Primary

23

16

 Metastatic

23

16

Age (years)

61.5 ± 19.5

57 ± 8.2

FIGO stage

  IIIA

2

0

  IIIC

14

16

  IV

7

0

FIGO grade

  Moderately differentiated

3

0

  Poorly differentiated

20

16

Histology

  Serous

22

16

  Endometrioid

1

0

 Median overall survival (OS) (months)

21 (range: 0–41)

111 (range: 82–195)

Fresh frozen (FF) samples

  Primary

17

0

  Metastatic

11

0

Paraffin-fixed (FFPE) samples

  Primary

6

16

  Metastatic

12

16

  Whole-exome sequenced

46

14

  RNA-sequenced

46

14

  1. Clinical characteristics of patients diagnosed with HGSC at FIGO stage III–IV. Tumor samples were collected from patients during primary cytoreductive surgery in Washington University in St. Louis.