Fig. 2: HCC tumor-bearing mice exhibited distinct microbiota diversity and composition. | Communications Biology

Fig. 2: HCC tumor-bearing mice exhibited distinct microbiota diversity and composition.

From: Tumor-mediated microbiota alteration impairs synaptic tagging/capture in the hippocampal CA1 area via IL-1β production

Fig. 2

Feces samples were collected from mock and tumor-bearing mice, 16S rRNA sequencing was performed to identify the microbiota species distributions in the samples (n = 10). a Average abundance of prevalent microbiota at the class level (left) and genus level (right) in the mock and tumor-bearing mice. b Comparison of alpha-diversity using ACE index, Observed species, Shannon index and Simpson index in mock mice compared to the tumor-bearing mice. c The Weighted Unifrac was plotted to show the beta diversity. d PCoA analysis based on the Unweighted Unifrac was plotted to show the beta diversity. e Taxonomic cladogram obtained from LEfSe analysis showing bacterial taxa that were differentially abundant in mock or tumor-bearing mice. Red indicates increased abundance in tumor-bearing mice; green indicates increased abundance in mock mice.

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