Fig. 5: Longitudinal evaluation of PLE and LZC in three CLIS participants from the CLIS dataset (fluctuations between different sessions).
From: Altered brain dynamics index levels of arousal in complete locked-in syndrome
The mean PLE (a) and LZC (c) distributions and their respective coefficients of variation (b, d) are represented using box plots for the three CLIS participants and also for the mean of the healthy controls group (n.b., multisession records in controls are missing). A progressive increase for mPLE (with a decrease for cvPLE) and a progressive decrease for mLZC (with an increase for cvLZC) are observed for the three CLIS participants compared to the average of the HC. PSD with standard error mean (e) showed a power spectrum close to the mean of HC for participant #11 (transition to CLIS occurred during the EEG recording period), while PSD of participants #9 (1 year in CLIS) and #11 (5 years in CLIS) showed an overall steep decline compared to HC, with higher values in slow frequencies (1–8 Hz), a slowing of alpha peaks in the delta-theta range and a loss of power in higher frequencies (10–40 Hz). Source data are provided in Supplementary Data 1.
