Fig. 6: Evaluation of PLE and LZC in the ALS dataset.
From: Altered brain dynamics index levels of arousal in complete locked-in syndrome
The mean distribution of PLE (a) and LZC (c) and their respective coefficients of variation (b, d) are represented using violin plots and box plots for the two CLIS patients, the LIS participant, the 14 non-LIS ALS participants, and the healthy controls. A significant increase for mPLE (with a decrease for cvPLE) and a significant decrease for mLZC (with an increase for cvLZC) are observed only for the CLIS participants compared to the other groups through z score normalisation. Instead, the results observed in the HC, non-LIS, and LIS groups were not significant by non-repeated measures test (HC and non-LIS) and z score normalisation (the single LIS patient), except for a significant decrease for cvLZC in participants without LIS compared to HC. PSD with standard error mean (e) showed a steep overall decline in CLIS compared to HC, non-LIS, and LIS, with higher values in slow frequencies (1–8 Hz), a slowing of alpha peaks in the delta-theta range, and a power slope in the higher frequencies (10–40 Hz). Source data are provided in Supplementary Data 1.
