Fig. 10: Insulin and estrogen signaling in inspiration4 astronaut PBMC and skin samples.
From: Spaceflight induces changes in gene expression profiles linked to insulin and estrogen
a Percent overlap of genes associated with insulin and estrogen signaling in single cell RNA-seq PBMC data, by cell types. b Log2 Female to male gene ratios from panel c. Fold changes of enrichment scores in response to spaceflight by sex, postflight collection time points, and cell types, PBMC data. The color scale bar represents fold change values are relative to pre-flight. d Fold changes of enrichment scores in postflight relative to preflight time point, by sex and tissue compartments (OE outer epidermis, IE inner epidermis, OD outer dermis, VA vasculature) in skin biopsy data. The color scale bar represents fold change values.
