Table 1 Summary of sequences and structures of anti-SARS-CoV-2 antibodies and nanobodies.

From: SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

Origin/Source

Sequences

Structures * (PDB IDs)

Total antibodies

6746

340

  Human (patient or vaccinee)

6321

250

  Mouse (immunized/humanized)

165

40

  Phage display library or engineered

225

33

  Undefined

35

25

Total nanobodies

620

83

  Immunized (alpaca/camel/llama#)

332 (123/18/189)

50 (16/5/27)

  Phage display library

276

23

  Undefined

14

12

  1. The sequences and origin/source are collected in CovAbDab26, as of 12/20/2022. The number of structures of antibodies and nanobodies in complex with RBD or spike protein are downloaded from PDB.
  2. *Unique non-redundant structures determined either by X-ray or cryo-EM as listed in the PDB.
  3. #This includes two sequences/structures from mice engineered to express llama Nb genes77.
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