Fig. 5: Second-generation pipeline to identify COMF mutations in cancer mutational data.
From: Mining cancer genomes for change-of-metabolic-function mutations
a Number of total missense mutations by year. b Number of 3 + , 4 + , … 9 + , 12+ recurrent mutations with COSMIC v59 (left) vs. COSMIC v96 (right) mutational data evaluated using METIS. An exponential Malthusian growth regression was used. c Schematic showing pipeline, with number of mutations filtered at each step.
