Table 2 Parameters used in the vertex model.

From: The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunction

Parameter

Symbol

Value

 

Average cell length

 

8.2 μm

 

Cell target area

A0

290 μm2

69

Cell contractility

Γ/K

0.04

74

Line tension

Λ/K

3.7 × 10−9 m−1

Estim.

Mutant E-cadherin line tension

Λ/K

4.6 × 10−6 m−1

Estim.

Viscous time-scale

ν/K

1.01 × 109 s/m

74