Table 1 Summary of link detection by the proposed method on the six sets of AlphaFold-Multimer (v2.2.0) predicted structures.
From: Topological links in predicted protein complex structures reveal limitations of AlphaFold
Species | All predicted structures | Top-ranked structures | |||||
|---|---|---|---|---|---|---|---|
Bait proteins | Prey proteins | Total | Linked | Percentage | Total | Linked | Percentage |
Experimental PPI of H. sapiens | 21025 | 641 | 3.05% | 841 | 21 | 2.50% | |
Experimental PPI of D. melanogaster | 20700 | 565 | 2.73% | 828 | 16 | 1.93% | |
E. coli | E. coli | 10000 | 60 | 0.60% | 400 | 4 | 1.00% |
H. sapiens | H. sapiens | 18000 | 65 | 0.36% | 720 | 3 | 0.42% |
H. sapiens | SARS-CoV-2 | 14350 | 169 | 1.18% | 574 | 5 | 0.87% |
Measles virus & Human herpesvirus | H. sapiens | 6425 | 58 | 0.90% | 257 | 3 | 1.17% |
Total | 90500 | 1558 | 1.72% | 3620 | 52 | 1.44% | |
