Fig. 2: ta-ILC2s is a heterogeneous population with pro-inflammatory phenotypes, as a response to a developing neoplastic disease at week 2 and 3. | Communications Biology

Fig. 2: ta-ILC2s is a heterogeneous population with pro-inflammatory phenotypes, as a response to a developing neoplastic disease at week 2 and 3.

From: A diversity of novel type-2 innate lymphoid cell subpopulations revealed during tumour expansion

Fig. 2

A Graph-based clustering of ILC2s using Seurat R package. t-distributed stochastic neighbor embedding (tSNE) plots were generated to visualize graph-based clustering of cells. Both naïve and ta-ILC2s are merged in the analysis to reveal common subpopulations of ILC2s. B Heatmap with the top ten differentially expressed genes per cluster, ranked by log-transformed fold change in expression levels in each cluster compared with all other clusters. Heterogeneity is observed in the overall ILC2 population (ta-ILC2 and naive ILC2) with differentially expressed genes.

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