Fig. 2: Characteristics of in vivo radiosensitivities of different cell types in intestine. | Communications Biology

Fig. 2: Characteristics of in vivo radiosensitivities of different cell types in intestine.

From: Single-cell map of dynamic cellular microenvironment of radiation-induced intestinal injury

Fig. 2

a Bar plots showing the fraction of cells originating from the control and day 1 groups in each cluster. Only the clusters that had >50 cells from the two groups and that showed no inter-individual difference (clusters with no more than 70% of cells from a single sample) were shown. Vertical dashed lines indicate the overall fraction of cells originating from the control group in all shown clusters. b Difference of hallmark pathway activities between stem cells from the control and day 1 (D1) groups. Shown are t values calculated in a linear modal comparing the pathway scores estimated by gene set variation analysis (GSVA) between cells from the two groups. c The same as (b) for macrophages from the control and day 1 groups. d Venn diagram showing the intersection of differentially expressed genes between cells from the control and day 1 groups for stem cells, macrophages, T cells, and enterocytes. e Top 10 significantly enriched gene ontology (GO) terms of 67 common differentially expressed genes for stem cells, macrophages, T cells, and enterocytes.

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