Fig. 2: Structural organization of archaeal GS. | Communications Biology

Fig. 2: Structural organization of archaeal GS.

From: Differences in regulation mechanisms of glutamine synthetases from methanogenic archaea unveiled by structural investigations

Fig. 2

All models are in the apo state and represented in cartoons. a Top view of one MtGS hexamer. b Side view of the MtGS dodecamer with one subunit shown in a transparent surface (cyan). c MtGS monomer with the main loops highlighted. The color coding of the loops is indicated in the box. The N- and C- terminal domains are colored light blue and cyan, respectively. d Top view of one MsGS hexamer. e The side view of the MsGS dodecamer with one subunit shown as a transparent surface (purple). f MsGS monomer with the main loops highlighted with the same color coding as in panel (c). The N- and C-terminal domains are colored lavender and purple, respectively. g Overlay of MtGS (cyan) and BsGS apo state (red, PDB 4LNN). h Overlay of MsGS (purple) and BsGS apo state (red). For panels (g, h) the star indicates the position of the loop deviating in both archaeal GS compared to BsGS. Mg atoms are displayed as green spheres.

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