Fig. 1: Determination of seven benzimidazole anthelmintics examined in this study.

a The top 20 drugs with high similarity scores with ABZ were identified using SIMCOMP, a similar compound search tool. Of these, seven benzimidazole anthelmintics including ABZ were selected for further analysis (highlighted in red). b The chemical structures of each drug are shown. The drugs had different substituents at the 5th position of the benzimidazole nucleus. The shared structure with ABZ is highlighted in red.