Fig. 1: Host genetic principal components (PCs) associated with the nasal microbial diversity and compositions.

a Correlation (R2) estimates of ten host PCs (PC1-PC10) with the nasal microbial diversity (Shannon and Simpson indices) and compositions (PCo1-PCo10), evaluated using a linear model. Red colours denoted the positive correlation and blue denotes the negative correlation. *p < 0.05, **p < 0.01 and ***p < 0.001. b, c indicate the correlations between the host genetic PC1 and the nasal microbial Shannon index (b) and Simpson index (c), respectively. d, e indicate the correlations between the host genetic PC2 and the nasal microbial Shannon index (d) and Simpson index (e), respectively. The individuals whose ancestry lived in the northern or the southern China were marked in red and blue, respectively. Grey dots represented individuals with the unknown (“NA”) ancestry information.