Fig. 2: Diffusion analysis of KRAS trajectories on the 8-lipid-supported lipid bilayer in the absence of RBDCRD (left) and in the presence of RBDCRD (right).
From: Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane
The top panel shows the three-state diffusion model predicted by Hidden Markov Modeling analysis of the trajectories. The green color represents the fast state, the orange color represents the intermediate state, and the red color represents the slow state. The radius of the circle is drawn proportional to the fractional occupancy in the state, and the width of the arrows is drawn proportional to the transition probability between the two states. The D represents the diffusion coefficient and τ represents the residence time in the state. The bottom panel shows the mean square displacement plots.
