Fig. 4: RBDCRD binding to the membrane tethered KRAS increases confinement on various lipid compositions.
From: Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane
Mean square displacement (MSD) plots calculated from the trajectories of KRAS diffusing on various types of lipid bilayers collected before and after addition of RBDCRD represented by long-dash-dot lines and solid lines respectively. a The blue line represents POPC/POPS (20%), b the red line represents POPC/PIP2 (5%), c the black line represents the 6-lipid bilayers (POPC/PAPC/PAPE/DIPE/PAPS/PIP2), d the yellow line represents the 7-lipid bilayers (POPC/PAPC/PAPE/DIPE/PAPS/PIP2/DPSM), and e the green line represents the 8-lipid bilayers (POPC/PAPC/PAPE/DIPE/PAPS/PIP2/DPSM/Cholesterol). The corresponding raw data with associated errors are tabulated in Supplementary Tables 4, 5.
