Fig. 5: Diffusion analysis of KRAS in the presence of the dimer-inducing compound, BI2852, and clustering reagent, DSSO, compared to KRAS by itself and in the presence of RBDCRD.
From: Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane
a Mean square displacement plots of KRAS on 2-lipid (blue) and b 8-lipid (green) bilayer. The Fig. 5b is KRAS diffusion on a 8-lipid bilayer shown on different y-axis. KRAS diffusion without any treatment is represented by long-dash-dot line and after treatment with BI2852 is represented by a dotted line, DSSO by short-dash-dot line, and RBDCRD by a solid line. The corresponding raw data with associated errors are tabulated in Supplementary Table 6, 7.
