Fig. 9: The secondary structure of CRD changes with membrane insertion.
From: Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane
a The average β-strand length in loops 1 and 2 of the CRD as a function of dz. b Histogram of the populations of β-strand length as a function of dz. c Example orientations of the KRAS-RBDCRD complex at different dz values. KRAS is shown in blue, RBD in green, and CRD in yellow. The headgroups of the lipid bilayer leaflets are shown as cyan surfaces. Examples of hydrogen bonding networks are shown inset.
