Fig. 3: Comparison of repeat unit sugars transferred by BP-Pols in GT125.
From: Diversity of sugar-diphospholipid-utilizing glycosyltransferase families
The transferred repeat unit structures (in SNFG representation) are shown on a phylogenetic tree of BP-Pols in family GT125. There is an overall similarity between all the transferred sugars in the family and the similarity appears to correlate with the tree structure, i.e., BP-Pol sequence similarity. In particular, the ends of the repeat units (+1 and -1 subsites) appear to be often conserved, whereas there is more variety in the central region where the enzyme does not interact with the sugar. Note that the +1 site corresponds to the non-reducing end of the depicted sugar structures and the -1 site corresponds to the reducing end. Notably, the family contains BP-Pols from distant taxonomic origin and that yet transfer similar repeat units.
