Fig. 8: Structural superimpositions of members of different functional classes belonging to the same clans.
From: Diversity of sugar-diphospholipid-utilizing glycosyltransferase families
a Superimposition of O-Lig in cyan (GT121, PDB: 7TPG) and AlphaFold model of BP-Pol in pink (GT126, Genbank accession: AAM27615.1) showing that the conserved Glu in the BP-Pol aligns with the conserved His in the O-Lig, which has been proposed to activate the acceptor21 (RMSD 5.3 Å over 192 residues, sequence identity 20.8% over 485 residues). b Structural superimpositions of AlphaFold models of ECA-Pol in cyan (GT120, Genbank accession: ACH50550.1) and BP-Pol in pink (GT134, Genbank accession: CAI32772.1) illustrating structural similarity and co-localization of the conserved residues (RMSD 5.4 Å over 360 residues, sequence identity 17.1% over 543 residue).
