Fig. 6: Sequence-wise and family-wise evaluation of KnotFold and nine other RNA secondary structure prediction approaches.

a The overall F1 scores of predicted structures by various approaches over TS0 (1305 RNAs). b Head-to-head comparison of built structures of SPOT-RNA and KnotFold over TS0. c Head-to-head comparison of built structures of SPOT-RNA and KnotFold over pseudoknot targets in TS0. d The overall F1 scores of predicted structures by various approaches over RfamNew (472 RNAs). e Head-to-head comparison of built structures of SPOT-RNA and KnotFold over RfamNew. f Head-to-head comparison of built structures of SPOT-RNA and KnotFold over pseudoknot targets in RfamNew.