Fig. 1: The amount of microdiamonds increases in cells with time.
From: Cell-particles interaction – selective uptake and transport of microdiamonds
a Few microdiamonds (MDs) (red) are inside the cell (green) after 0.5 h of incubation. (b), c After 3 and 6 h, the amount of MDs increased with the incubation time. After 24 h (d), most MDs accumulate around the nucleus (blue). e Orthogonal side view of a cell with MDs inside the cell. Replications and number of cases for (a–d) are 6 and 45, respectively. f Live transfected cell with EGFP–F-tractin at the beginning of uptake. g Panels 1 to 6 are the time frames of the magnified area, marked as a white square in (f). Panels 1 and 2 show how the cell finds MDs employing protrusions: the cell extends the protrusions and creates lamellipodia to probe the particles (3,4). Finally, it is displayed in (5,6) that how the cell uptakes the particles inside. This process happens 16 h after adding the particles, and the time interval between images is 15 min. Replications and number of cases for (f–g) are 3 and 15, respectively.
