Fig. 7: Molecular modeling of immune complexes assembled on SCs. | Communications Biology

Fig. 7: Molecular modeling of immune complexes assembled on SCs.

From: Molecular architecture and platelet-activating properties of small immune complexes assembled on heparin and platelet factor 4

Fig. 7

A representative conformation of the dp100·(PF4)3·KKO2 complex obtained by docking two KKO Fab segments to the dp100·(PF4)3 complex followed by a 500 ns MD simulation and energy minimization. Both Fab segments in the energy-minimized structure were extended to the full-length IgG molecules followed by another cycle of energy minimization.

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