Fig. 1: Effects of miR-221-3p on wound healing in normal and diabetic mice. | Communications Biology

Fig. 1: Effects of miR-221-3p on wound healing in normal and diabetic mice.

From: MicroRNA-221-3p inhibits the inflammatory response of keratinocytes by regulating the DYRK1A/STAT3 signaling pathway to promote wound healing in diabetes

Fig. 1

Representative photomicrographs (a) and summary data (b, c) showing changes in the area of excisional wounds on days 0, 2, 4, 8, and 10 in normal mice injected with either miRNA mimic negative control (Ctrl) or miR-221-3p agomir (miR-221-3p) and diabetic mice injected with either miRNA mimic negative control (DM-Ctrl) or miR-221-3p agomir (DM-miR-221-3p). The smallest scale division of the ruler is 1 mm in a. Data are presented as mean ± SEM, n = 7–8. *P < 0.05, **P < 0.01 for Ctrl vs. miR-221-3p. #P < 0.05, ##P < 0.01 for DM-Ctrl vs. DM-miR-221-3p.

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