Table 1 Overview of the proteomic and transcriptomic studies of different protist organisms infected by their respective viruses

References	Protist organism	Virus	Technique	Time post infection	FoldChange	Down	Up
Rodrigues et al. (2020)¹³⁷	A. castellanii	Marseillevirus	RNAseq	0, 1, 2, 4, 5, 6, 8, 10, and 12HPI	<−1 and >1	28	19
Legendre et al. (2015)⁶²	A. castellanii	Mollivirus sibericum	LC-MS/MS	0 to 6HPI	<−2 and >2	38	30
Zhang et al. (2021)¹³⁸	A. castellanii	Medusavirus	RNAseq	8 to 16HPI	<−0.445 and >0.364	7970	2657
Moniruzzaman et al. (2018)¹⁶⁰	A. anophagefferens	Aureococcus anophagefferens virus	RNAseq	5 min	<−1.5 and >1.5	588	412
				30 min		≈ 865	≈ 505
				1HPI		82	0
				6HPI		≈ 1060	≈ 690
				12HPI		≈ 1260	≈ 1260
				21HPI		≈ 1430	≈ 1620
Poimala et al. (2022)¹³⁸	Phytophthora cactorum	PcBV1 & 2	RNAseq	-^a	<−2 and >2	23	10
Poimala et al. (2022)¹³⁸	Phytophthora cactorum	PcBV1 & 2	Nanoflow reverse-phase LC-MS	-^a	<−1.19 and >1.37	17	36
Provenzano et al. (1997)¹⁷¹	T. vaginalis	TVV	2D	-	-	41	47
He et al. (2017)¹⁷⁴	T. vaginalis	TVV	iTRAQ labeling	-	<−1 and >1	21	29
Rada et al. (2022)¹⁷⁵	T. vaginalis (exossome vesicle)	TVV	LFQ-MS	-	<−2 and >2	55	20

“FoldChange” means threshold utilized by each study to determine when a protein or transcript presents increased expression (upregulated - “up”) or decreased expression (downregulated - “down”). Other protists are not included on this table since information on the number of deregulated proteins or transcripts was not the focus of the publication or this data was not provided.
^aThe virus was removed from the protist strain, thus there was no time post-infection.

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