Fig. 5: Dysregulation of genes in the Dlk1-Dio3 imprinted domain in the labyrinth of Gtl2 polyA knock-in placentas at E12.5. | Communications Biology

Fig. 5: Dysregulation of genes in the Dlk1-Dio3 imprinted domain in the labyrinth of Gtl2 polyA knock-in placentas at E12.5.

From: Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature

Fig. 5

a–e In situ hybridization results show the expression pattern of Dlk1, Gtl2, Rtl1, miR-127 and Rian in the labyrinth of Gtl2 polyA knock-in and WT placentas, separately. Black arrows indicate gene expression normally in WT and PKI vasculature and red arrows indicate upregulated or downregulated gene expression in MKI and HOMO vasculature. In (a–e), scale bars: 50 μm.

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