Table 1 IC50 concentration ( ± SD) at 48 h in the presence and absence of NAC (0.5 mM)

From: Platinum iodido drugs show potential anti-tumor activity, affecting cancer cell metabolism and inducing ROS and senescence in gastrointestinal cancer cells

 

AGS

MKN45

PANC1

NAC (-)

NAC (+)

NAC (-)

NAC (+)

NAC (-)

NAC (+)

CDDP

26.67 ± 2.21

22.65 ± 4.03

9.45 ± 1.10

10.23 ± 1.56

12.33 ± 1.16

9.46 ± 1.29

I5

38.19 ± 3.50

>100

28.70 ± 1.03

>100

18.16 ± 5.06

>100

I6

51.52 ± 3.68

>100

56.75 ± 1.53

>100

18.84 ± 10.29

>100

  1. N = 3
Back to article page