Fig. 1: Characterization of SCA1-iPSC-derived Purkinje cells. | Communications Biology

Fig. 1: Characterization of SCA1-iPSC-derived Purkinje cells.

From: Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage

Fig. 1

Immunocytochemistry of iPSC-derived Purkinje cells with Calbindin, the specific marker of Purkinje cells. The lower left graph compares mature Purkinje cell numbers and the lower right graph compares Purkinje cell neurite lengths between cells differentiated from SCA1-iPSCs and normal iPSCs. Eight visual fields from two independent wells were observed. The two-tailed Student’s t-test was used for statistical examination. The box plot shows the median and 25–75th percentile, and whiskers represent data outside the 25–75th percentile range.

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