Fig. 3: p53/Sirt1/ATG7 axis and ATG7 epigenetic modification.
From: Insights on E1-like enzyme ATG7: functional regulation and relationships with aging-related diseases
It has been reported that ATG7 is regulated by epigenetic modifications of acetylation, deacetylation, and ubiquitination. p53/miR-155/Sirt1 axis forms a autophagy-regulating loop with ATG7.
