Fig. 3: Effects of V11A on pneumococcal morphology, chain length and transformation. | Communications Biology

Fig. 3: Effects of V11A on pneumococcal morphology, chain length and transformation.

From: Klebsiella pneumoniae peptide hijacks a Streptococcus pneumoniae permease to subvert pneumococcal growth and colonization

Fig. 3

a Microscopy images of pneumococci to assess pneumococcal cell morphology. Representative images of S. pneumoniae strains D39, 106.66, 208.41 after incubation with or without 0.5 mg/ml peptide V11A for 2.5 h taken at 100x magnification. Scale bar indicates 2 µm for all images. b Chain length of S. pneumoniae strains D39, 106.66, 208.41. Results represent chain length measurements of three independent experiments after incubation with or without 0.5 mg/ml peptide V11A for 2.5 h, each box represents length measurements of >1200 bacterial chains, *** indicates p value < 0.001 by two-sided Wilcoxon rank sum test for all comparisons. c Transformation rate of S. pneumoniae strain D39 without or with 0.5 mg/ml peptide V11A or control peptide (V11A with amino acid difference at position 4). Results represent at least five independent experiments for each condition represented by grey dots, **** indicates p value  ≤ 0.0001 by t-test.

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