Fig. 4: Effect of peptide V11A on pneumococcal transcriptome. | Communications Biology

Fig. 4: Effect of peptide V11A on pneumococcal transcriptome.

From: Klebsiella pneumoniae peptide hijacks a Streptococcus pneumoniae permease to subvert pneumococcal growth and colonization

Fig. 4

Genetic interaction network of significantly downregulated (log2FC ≤ −1.25) and upregulated (log2FC ≥ 1.25) genes in S. pneumoniae strain D39 after 15 min of incubation with 0.5 mg/ml peptide V11A. Interactions between 2 genes (nodes) are depicted as a line (edge) and were imported from the STRING database. Nodes are colour-coded according to the log2FC, with blue representing negative log2FC (downregulated) and red positive log2FC (upregulated). We highlighted Gene Ontologies or keywords of groups of genes in the background.

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