Fig. 2: Gut microbiota induced by environmental HTH. | Communications Biology

Fig. 2: Gut microbiota induced by environmental HTH.

From: High temperature and humidity in the environment disrupt bile acid metabolism, the gut microbiome, and GLP-1 secretion in mice

Fig. 2

a The pancreatic β cell mass, indicated by insulin immunofluorescence staining, was significantly expanded at 14 days after HTH treatment compared to NC group. The arbitrary units (AU) indicating the ratio of mean gray value to area were shown in columns. Scale bars = 40 μm. *P < 0.05 by two-tailed Student’s t test. Error bars represent ±s.d. Alpha diversity was applied to analyze the complexity of species of the NC group and HTH group. b Indices of Simpson and c Shannon, as well as d OUT numbers, are displayed. Error bars represent ±s.d. e PCA at the OTU level. The PCA of all the samples was based on the relative abundance of the OTUs. Percentiles represent the contributions of principal components to differences among samples. f The composition gut microbiota abundance at phylum level. g The ratio of Firmicutes/ Bacteroidetes. h, i The gut microbiota with differential abundance at genera level at day 7 and day 14 after HTH treatment. n = 6 mice for each group. *P < 0.05, **P < 0.01 by two-tailed Student’s t test. Error bars represent ±s.d.

Back to article page