Fig. 5: Ileal proteomics analysis. | Communications Biology

Fig. 5: Ileal proteomics analysis.

From: High temperature and humidity in the environment disrupt bile acid metabolism, the gut microbiome, and GLP-1 secretion in mice

Fig. 5

a Heat map indicates the differential expressed protein (DEP) with a criteria of change folds >1.2 or <0.83 and p-value < 0.05. b Volcano plot indicates DEPs with the above criteria and the top 3 enriched proteins and reduced proteins were labeled. c Relative abundance of FXR regulated protein. n = 3 for each group. *P < 0.05, **P < 0.01 by two-tailed Student’s t test. Error bars represent ±s.d. d The level of GLP-1 after treated with LCA, and FXR inhibitor in vitro. n = 3 for each group, **P < 0.01 by one-way ANOVA. Error bars represent ±s.d. Statistical significance was evaluated using p-values adjusted for multiple comparisons with the FDR method.

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