Fig. 7: Expression of several clock genes is reduced in male and female RDHE DKO mice and the cycling pattern of Notch1 is altered. | Communications Biology

Fig. 7: Expression of several clock genes is reduced in male and female RDHE DKO mice and the cycling pattern of Notch1 is altered.

From: Epidermal retinol dehydrogenases cyclically regulate stem cell markers and clock genes and influence hair composition

Fig. 7

Using samples from PD50 (n = 3), qPCR was performed for molecular clock genes for (a) females and (b) males. In (c), Notch1 was examined across all PDs due to its importance in hair cycle progression. All data are presented as the mean, with error bars representing SEM. Clock genes at PD50 were analyzed via a t-test and Notch1 was analyzed with a two-way ANOVA. Black letters indicate significant differences by a Tukey’s post hoc for a main effect of PD. Asterisks indicate significant differences between genotypes. *p < 0.05; **p < 0.01; ***p < 0.001.

Back to article page